Cell therapy may provide off-the-shelf treatment for cancer patients with BK virus-associated hemorrhagic cystitis A Phase II trial led by researchers at found that BK virus (BKV)-specific T cells from healthy donors were safe and effective as an off-the-shelf therapy for BKV-associated hemorrhagic cystitis (BKV-HC), a painful complication common after allogeneic stem cell transplants for patients with leukemia or lymphoma. The study was published today in the Journal of Clinical Oncology. Infusion of T cells targeting BKV resulted in rapid responses, […]
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Study shows protein inhibitor as potential treatment approach for common mutations found in non-Hodgkin lymphomas
Findings may create immunotherapy options for lymphomas caused by CREBBP mutations HOUSTON ― A study at The University of Texas MD Anderson Cancer Center demonstrated a potential new approach to treating two of the most common subtypes of lymphoma through manipulation of molecular programs controlled by the cAMP-response element binding protein (CREBBP). Mutations of CREBBP are frequently found in follicular lymphoma and diffuse large B-cell lymphomas (DLBCL), and allow malignant cells to hide from the immune system. Study results were published in the […]
MD Anderson study shows key enzyme linked to therapy resistance in deadly lung cancer
Two existing therapies may have potential for further study in treatment of EGFR-mutant non-small cell lung cancers Researchers at The University of Texas MD Anderson Cancer Center have identified a link between an enzyme tied to cancer formation and therapy resistance in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC). They believe two existing therapies may hold promise for clinical studies for this deadly and common lung cancer for which relapse often occurs […]
Sarah P. Bernhardt, Ph.D., Named President & Ceo Of The Bayou Preservation Association
HOUSTON (August 20, 2018) – The Bayou Preservation Association has named Sarah P. Bernhardt, Ph.D., as its new President & CEO, effective immediately. She will lead the organization in realizing its vision of a network of healthy bayous, streams and watersheds through conservation, preservation, restoration and responsible watershed management. As head of the nonprofit, she will work in strategic partnership with the board of directors, advocate for its mission, programs and projects and help develop science-based […]
Genetically enhanced, cord-blood derived immune cells strike B-cell cancers
HOUSTON – Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia. The team’s preclinical research shows that natural killer cells derived from donated umbilical cords can be modified to seek and destroy some types of leukemia and […]