Cell therapy may provide off-the-shelf treatment for cancer patients with BK virus-associated hemorrhagic cystitis A Phase II trial led by researchers at found that BK virus (BKV)-specific T cells from healthy donors were safe and effective as an off-the-shelf therapy for BKV-associated hemorrhagic cystitis (BKV-HC), a painful complication common after allogeneic stem cell transplants for patients with leukemia or lymphoma. The study was published today in the Journal of Clinical Oncology. Infusion of T cells targeting BKV resulted in rapid responses, […]
Katy Rezvani
Genetically enhanced, cord-blood derived immune cells strike B-cell cancers
HOUSTON – Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia. The team’s preclinical research shows that natural killer cells derived from donated umbilical cords can be modified to seek and destroy some types of leukemia and […]