Absent p53

Absent p53, oral cancers recruit and reprogram nerves to fuel tumor growth

Nature paper sheds light on poorly understood hallmark of cancer; points to possible treatment HOUSTON ― Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting them to the tumor, where they fuel growth and cancer progression, researchers from The University of Texas MD Anderson Cancer Center report in the journal Nature today. By cracking the mechanism that launches neuronal invasion of tumors, a known marker of poor prognosis […]