achieves durable clinical benefit in early trial

KRAS inhibitor sotorasib appears safe, achieves durable clinical benefit in early trial

David S Hong, M.D.

Phase I study encouraging for patients with advanced cancers and KRAS G12C mutations ABSTRACT: 1257O HOUSTON ― In a Phase I clinical trial for patients with advanced solid cancers marked by KRAS G12C mutations, the KRASG12C inhibitor sotorasib (AMG 510) resulted in manageable toxicities and […]