Small cell lung cancer may respond to combination of immunotherapy and DNA damage repair inhibitors

Small cell lung cancer may respond to combination of immunotherapy and DNA damage repair inhibitors

Preclinical research finds new approach to treating aggressive cancer unresponsive to immunotherapy alone Watch Lauren Byers, M.D discuss the study’s findings. HOUSTON ― Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and targeted therapies that block normal DNA damage repair (DDR) achieved significant tumor regression in mouse models of small cell lung cancer (SCLC), suggesting a promising new approach for treating patients with this aggressive cancer. The preclinical research, published today in Cancer […]